Here's a domestic sitcom with a twist.
Grindl, a 1-year wonder for NBC in 1963-4, cast Imogene Coca in the title role of a talkative woman who went from job to job, only because her primary employer was an employment agency that filled vacant jobs for various employers. That's still happening today, but it's not as prevalent.
Creator-producer David Swift already had a hit with another domestic sitcom for Screen Gems with Hazel, who at least had a steady job. Grindl depicted just the opposite. In Grindl's case, she got into some of the same kinds of situations that Hazel would find herself in occasionally, all quite by chance or accident.
Here's the intro: