This has one of the oddest titles ever for a game show. By a wide margin.
How's Your Mother-in-Law? (originally Here Come the Mother-in Laws, as you'll see in the pilot) lasted just three months (December 1967-March 1968) on ABC, and with a title like that, it could only come from the warped mind of producer Chuck Barris (The Dating Game, The Newlywed Game). Wink Martindale is the host.
While The Gong Show, The Dating Game, & The Newlywed Game have each been revived multiple times, you have to imagine even Barris was so embarrassed by this flop, such that he never revisited the idea again.