"Bark at The Moon" is the title song from Ozzy Osbourne's 1983 CD. Ozzy presents himself as a mad scientist who ingests a formula, turning him into a werewolf, as depicted on the album cover. The makeup was designed by Rick Baker ("An American Werewolf in London", among others). Carmine Appice (ex-Vanilla Fudge), who'd later play on tour with Osbourne, appears in the video, but didn't play on the album.
Yes, the early part of the video was inspired by Robert Louis Stevenson's Dr. Jekyll & Mr. Hyde, and that tome also was parodied by Men at Work ("Dr. Hekyll & Mr. Jive") a year earlier.