From the 1992 DTV Time Out: The Truth About HIV:
Who'd ever thought that Jaleel White, aka Steve Urkel from Family Matters, actually had some skills as a rapper?
White was one of a number of young stars recruited for Time Out, directed by Malcolm Jamal-Warner (The Cosby Show), who appears near the end of the video. The full length production also features Tom Cruise, Mayim Bialik (Blossom) and hosts Earvin "Magic" Johnson and Arsenio Hall.
But, check "Contents Under Pressure", a 90 second cautionary tale about premarital sex.